The Supercomputer MACH-2: Use Cases

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Use Case: Comprehensive meta-analysis of available marker gene datasets from black soldier fly (Hermetia illucens) larvae

Scientific Groups and Collaborations Description of the Application

As the flagship species of an emerging insect biotechnology with the goal to convert organic wastes into a source of insect-based protein and fat, the black soldier fly (BSF; Hermetia illucens) has awaken popular interest in science and industry. Research showed, a complex network of microbial gut communities strongly contributes to waste degradation processes and shapes the larval environment. However, the lack of a best practice approach in preparing and analyzing raw sequence data affects the informative value and reproducibility between studies. Thus, a comprehensive re-analysis of published data following a standardized protocol in the context of a meta-analysis could drastically improve comparability and enable robust conclusions across studies.

The volume of sequencing data and the iterative preprocessing optimization require for high computational effort, creating the need for parallelization of analysis tools on high-performance computing (HPC) platforms.

Published Scientific Literature

Relevant Links

JKU Scientific Computing Administration